To critically examine the epidemiologic evidence linking work related exposure to osteoarthritis (OA) of the hip and knee.
We investigated MEDLINE and EMBASE 1966-1994 with search terms osteoarthritis, osteoarthrosis, arthrosis ; risk factors, exposure ; occupational diseases, agricultural workers'diseases, work.
From 123 original studies on risk factors for OA, 17 studies were identified as providing a comparison group and relating the presence or absence of radiologically diagnosed OA to occupational factors.
The quality of the methodology of each study was evaluated independently by 4 reviewers using a standardized protocol.
Common methodological problems were encountered in areas such as representativeness, recall of exposure, and evaluation of exposure and outcome.
These problems often made a cause-effect relationship difficult to interpret.
However, 7 of the 17 studies met our criteria for good methodological quality.
A critical analysis of their results led to the following conclusions : (1) A consistently positive relationship exists between work involving knee bending and knee OA in men (range of odds ratios : 1.4-6). (2) The evidence suggesting a relationship between knee OA and occupational exposure in women is inconclusive. (3) A consistently positive but weak relationship exists between work related exposure (i.e., farming in particular) and hip OA in men. (...)
Mots-clés Pascal : Arthrose, Genou, Hanche, Facteur risque, Maladie professionnelle, Homme, Exposition professionnelle, Epidémiologie, Système ostéoarticulaire pathologie, Arthropathie, Maladie dégénérative, Médecine travail
Mots-clés Pascal anglais : Osteoarthritis, Knee, Hip, Risk factor, Occupational disease, Human, Occupational exposure, Epidemiology, Diseases of the osteoarticular system, Arthropathy, Degenerative disease, Occupational medicine
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0431632
Code Inist : 002B15A. Création : 19/12/1997.