Objectives-To ascertain whether certain occupations are associated with laryngeal or hypopharyngeal cancer.
Methods-A hospital based case-control study was carried out in 15 hospitals in France.
It included 528 male cases diagnosed between January 1989 and April 1991, and 305 male controls with various other types of cancer.
Interviews were carried out to obtain lifetime job histories and information on potential confounders.
Logistic regression was used to compute the odds ratios (OR) for each of about 80 occupations and industries.
There was an excess risk of laryngeal and hypopharyngeal cancer among service workers (OR 2.2,95% confidence interval (95% CI) 1.3 to 3.9), agricultural and animal husbandry workers (OR 1.6,95% CI 0.9 to 2.8), miners and quarrymen (OR 2.0,95% CI 0.9 to 4.3), plumbers and pipe fitters (OR 2.6,95% CI 0.8 to 8.1), glass formers and potters (OR 4.3,95% CI 1.0 to 18), transport equipment operators (OR 1.5,95% CI 1.0 to 2.5), and unskilled workers (OR 1.7,95% CI 1.0 to 2.9).
Analysis by industrial branch showed an excess risk for coal mining (OR 2.1,95% CI 1.1 to 4.1), manufacture of metal products (OR 1.9,95% CI 1.0 to 3.3), and administration and sanitary services (OR 1.7,95% CI 1.1 to 2.5). (...)
Mots-clés Pascal : France, Europe, Epidémiologie, Exposition professionnelle, Tumeur maligne, Hypopharynx, Larynx, Médecine travail, Homme, Etude cas témoin, Carcinogène, ORL pathologie, Pharynx pathologie, Larynx pathologie
Mots-clés Pascal anglais : France, Europe, Epidemiology, Occupational exposure, Malignant tumor, Hypopharynx, Larynx, Occupational medicine, Human, Case control study, Carcinogen, ENT disease, Pharynx disease, Larynx disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0430428
Code Inist : 002B10B01. Création : 19/12/1997.