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  1. Surveillance for Escherichia coli O157 : H7 infections in Minnesota by molecular subtyping.

    Article - En anglais

    Background Escherichia coli O157 

    H7 is a leading cause of diarrhea and the hemolytic-uremic syndrome.

    Current public health surveillance for E. coli O157 : H7 requires considerable resources ; traditional methods lack the sensitivity and specificity to detect outbreaks effectively.

    Methods During 1994 and 1995, the Minnesota Department of Health requested that all clinical isolates of E. coli O157 : H7 be submitted to our laboratory.

    Isolates were subtyped by pulsed-field gel electrophoresis (PFGE), and patients were interviewed about potential sources of infection.

    Results In 1994 and 1995,344 cases of E

    Coli 0157 : H7 infection were reported to the Minnesota Department of Health ; 317 (92 percent) were subtyped by PFGE, and 143 distinct PFGE patterns were identified.

    Ten outbreaks of E. coli O157 : H7 were identified ; these accounted for 56 (18 percent) of the 317 subtyped cases.

    Four outbreaks were detected solely as a result of subtype-specific surveillance.

    In 11 two-week periods, the number of reported cases of E. coli O157 : H7 doubled from the previous two weeks.

    In eight of these instances, the patterns identified were dissimilar and there were no outbreaks.

    Two of the remaining three increases resulted from multiple simultaneous outbreaks.

    Conclusions Subtype-specific surveillance for E


    Mots-clés Pascal : Escherichia coli, Enterobacteriaceae, Bactérie, Epidémiologie, Surveillance, Biologie moléculaire, Soustype, Evaluation, Electrophorèse, Minnesota, Etats Unis, Amérique du Nord, Amérique, Homme, Bactériose, Infection, Organisation santé, Activité biologique

    Mots-clés Pascal anglais : Escherichia coli, Enterobacteriaceae, Bacteria, Epidemiology, Surveillance, Molecular biology, Subtype, Evaluation, Electrophoresis, Minnesota, United States, North America, America, Human, Bacteriosis, Infection, Public health organization, Biological activity

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0429277

    Code Inist : 002B05B02F. Création : 19/12/1997.