We asked whether pediatric renal transplant recipients, subgrouped by age, differed in the percentage and number of hospital readmissions and in the incidence of infectious complications post transplant.
Between 1 August 1985 and 31 October 1993, a total of 164 patients<18 years of age underwent primary transplants, with cyclosporine-based immunosuppression, at the University of Minnesota.
The percentage of readmissions (P=NS), the mean number of readmissions (P=NS), and the length of hospital stay during readmission (P=NS) did not differ significantly among age groups.
The overall incidence of acute rejection was greater in those =2 years than those<2 years (P=0.002), and in living donor recipients =2 years versus those<2 years (P=0.02).
The incidence of bacterial infection (<2 years, 87% ; 2-5 years, 72% ; 6-12 years, 51% ; 13-17 years, 40%) was greater in younger recipients (P=0.0001).
The most common bacterial infection in recipients ¾5 years was Clostridium difficile-associated diarrhea ; in those>5 years, urinary tract infection.
The overall incidence of viral infection did not differ among groups (P=NS).
The most common viral infection in recipients ¾5 years was varicella and those>5 years, cytomegalovirus infection.
Risk factors for infection in the first 6 months post transplant included age<2 years and Solu-Medrol treatment for acute rejection. (...)
Mots-clés Pascal : Transplantation, Rein, Complication, Infection, Incidence, Relation, Age, Facteur risque, Evolution, Etude statistique, Enfant, Homme, Chirurgie, Appareil urinaire pathologie, Rein pathologie
Mots-clés Pascal anglais : Transplantation, Kidney, Complication, Infection, Incidence, Relation, Age, Risk factor, Evolution, Statistical study, Child, Human, Surgery, Urinary system disease, Kidney disease
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0428364
Code Inist : 002B25H. Création : 19/12/1997.