Complications by age in primary pediatric renal transplant recipients.
We asked whether pediatric renal transplant recipients, subgrouped by age, differed in the percentage and number of hospital readmissions and in the incidence of infectious complications post transplant.
Between 1 August 1985 and 31 October 1993, a total of 164 patients<18 years of age underwent primary transplants, with cyclosporine-based immunosuppression, at the University of Minnesota.
The percentage of readmissions (P=NS), the mean number of readmissions (P=NS), and the length of hospital stay during readmission (P=NS) did not differ significantly among age groups.
The overall incidence of acute rejection was greater in those =2 years than those<2 years (P=0.002), and in living donor recipients =2 years versus those<2 years (P=0.02).
The incidence of bacterial infection (<2 years, 87% ; 2-5 years, 72% ; 6-12 years, 51% ; 13-17 years, 40%) was greater in younger recipients (P=0.0001).
The most common bacterial infection in recipients ¾5 years was Clostridium difficile-associated diarrhea ; in those>5 years, urinary tract infection.
The overall incidence of viral infection did not differ among groups (P=NS).
The most common viral infection in recipients ¾5 years was varicella and those>5 years, cytomegalovirus infection.
Risk factors for infection in the first 6 months post transplant included age<2 years and Solu-Medrol treatment for acute rejection. (...)
Mots-clés Pascal : Transplantation, Rein, Complication, Infection, Incidence, Relation, Age, Facteur risque, Evolution, Etude statistique, Enfant, Homme, Chirurgie, Appareil urinaire pathologie, Rein pathologie
Mots-clés Pascal anglais : Transplantation, Kidney, Complication, Infection, Incidence, Relation, Age, Risk factor, Evolution, Statistical study, Child, Human, Surgery, Urinary system disease, Kidney disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0428364
Code Inist : 002B25H. Création : 19/12/1997.