Women sustaining myocardial infarction fare worse than men during hospitalization.
Reports on long-term survival in women surviving an acute myocardial infarction are controversial.
The Secondary Prevention Reinfarction Israeli Nifedipine Trial (SPRINT) registry includes 5,839 consecutive myocardial infarction patients who were hospitalized in 13 coronary care units in Israel between 1981 and 1983.
The authors examined sex differences in the long-term survival of 4,808 hospital survivors (1,120 women and 3,688 men).
Women exhibited a significantly poorer long-term survival than men.
After age adjustment, differences between men and women decreased, leaving a survival probability difference of 11% at the end of 12 years of follow-up.
In a subgroup analysis, women exhibited poorer survival than men in a comparison of patients with and without periinfarction congestive heart failure or a history of myocardial infarction preceding the index infarction.
The multivariate adjusted hazard ratios associated with female sex in diabetic and nondiabetic patients were 1.46 and 1.13, respectively.
In conclusion, a cumulative survival disadvantage for women in comparison with men is still evident after 12 years of follow-up.
The mortality difference is diminished but not erased after age adjustment or multivariate adjustment for confounders. (...)
Mots-clés Pascal : Infarctus, Myocarde, Homme, Femelle, Epidémiologie, Survie, Pronostic, Sexe, Long terme, Etude longitudinale, Mortalité, Israël, Asie, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie
Mots-clés Pascal anglais : Infarct, Myocardium, Human, Female, Epidemiology, Survival, Prognosis, Sex, Long term, Follow up study, Mortality, Israel, Asia, Cardiovascular disease, Coronary heart disease, Myocardial disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0427673
Code Inist : 002B12A03. Création : 19/12/1997.