Short-term effects of ambient oxidant exposure on mortality : A combined analysis within the APHEA project.
The Air Pollution and Health : a European Approach (APHEA) project is a coordinated study of the short-term effects of air pollution on mortality and hospital admissions using data from 15 European cities, with a wide range of geographic, sociodemographic, climatic, and air quality patterns.
The objective of this paper is to summarize the results of the short-term effects of ambient oxidants on daily deaths from all causes (excluding accidents).
Within the APHEA project, six cities spanning Central and Western Europe provided data on daily deaths and NO2 and/or O3 levels.
The data were analyzed by each center separately following a standardized methodology to ensure comparability of results.
Poisson autoregressive models allowing for overdispersion were fitted.
Fixed effects models were used to pool the individual regression coefficients when there was no evidence of heterogeneity among the cities and random effects models otherwise.
Factors possibly correlated with heterogeneity were also investigated.
Significant positive associations were found between daily deaths and both NO2 and O3.
Increases of 50 mug/m3 in NO2 (1-hour maximum) or O3 (1-hour maximum) were associated with a 1.3% (95% confidence interval 0.9-1.8) and 2.9% (95% confidence interval 1.0-4.9) increase in the daily number of deaths, respectively.
Stratified analysis of NO2 effects by low and high levels of black smoke or O3 showed no significant evidence for an interaction within each city. (...)
Mots-clés Pascal : Pollution air, Azote dioxyde, Ozone, Toxicité, Mortalité, Epidémiologie, Métaanalyse, Homme, Europe, Santé et environnement, Milieu urbain
Mots-clés Pascal anglais : Air pollution, Nitrogen dioxide, Ozone, Toxicity, Mortality, Epidemiology, Metaanalysis, Human, Europe, Health and environment, Urban environment
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0427560
Code Inist : 002B30A02A. Création : 19/12/1997.