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  1. Antiviral chemoprophylaxis after occupational exposure to human immunodeficiency virus : Why, when, where, and what.

    Article - En anglais

    PURPOSE 

    To update ophthalmologists on recent developments in the area of antiviral chemoprophylaxis after occupational exposure to human immunodeficiency virus (HIV).

    Background information is provided by which to make an informed decision about whether to initiate antiviral chemoprophylaxis against HIV infection..

    METHODS 

    We discuss why HIV postexposure prophylaxis should be considered ; when prophylaxis should be initiated ; where prophylaxis medications should be located in the operating or emergency room ; and what medications might be used and the factors influencing their selection.

    Recent provisional recommendations by the United States Centers for Disease Control and Prevention and the International AIDS Society-USA are reviewed along with literature dealing with antiviral chemoprophylaxis against HIV infection.

    RESULTS 

    Recommendations are made for specific antiviral chemoprophylaxis after occupational exposure to HIV based on the Centers for Disease Control and Prevention and the International AIDS Society-USA provisional recommendations.

    Uncertain areas and the minor discrepancies in these two reports are discussed.

    CONCLUSIONS 

    Prevention of HIV transmission after accidental occupational exposure is possible.

    Combination therapy is more effective than monotherapy in treating HIV infections. (...)

    Mots-clés Pascal : Ophtalmologie, Chirurgien, Exposition professionnelle, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Chimioprophylaxie, Antiviral, Prévention, Indication, Timing, Homme, Médecine travail

    Mots-clés Pascal anglais : Ophthalmology, Surgeon, Occupational exposure, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Chemoprophylaxis, Antiviral, Prevention, Indication, Timing, Human, Occupational medicine

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0427380

    Code Inist : 002B30B01B. Création : 19/12/1997.