Outcomes of single organism peritonitis in peritoneal dialysis : Gram negatives versus gram positives in the Network 9 Peritonitis Study.
The use of the « peritonitis rate » in the management of patients undergoing peritoneal dialysis is assuming importance in comparing the prowess of facilities, care givers and new innovations.
For this to be a meaningful outcome measure, the type of infection (causative pathogen) must have less clinical significance than the number of infections during a time interval.
The natural history of Staphylococcus aureus, pseudomonas, and fungal peritonitis would not support that the outcome of an episode of peritonitis is independent of the causative pathogen.
Could this concern be extended to other more frequently occurring pathogens ?
To address this, the Network 9 Peritonitis Study identified 530 episodes of single organism peritonitis caused by a gram positive organism and 136 episodes caused by a single non-pseudomonal gram negative (NPGN) pathogen.
Coincidental soft tissue infections (exit site or tunnel) occurred equally in both groups.
Outcomes of peritonitis were analyzed by organism classification and by presence or absence of a soft tissue infection.
NPGN peritonitis was associated with significantly more frequent catheter loss, hospitalization, and technique failure and was less likely to resolve regardless of the presence or absence of a soft tissue infection. (...)
Mots-clés Pascal : Péritonite, Bactériose, Infection, Homme, Dialyse péritonéale, Pronostic, Souche pathogène, Bactérie Gram positif, Bactérie Gram négatif, Etiologie, Epidémiologie, Abdomen pathologie, Epuration extrarénale
Mots-clés Pascal anglais : Peritonitis, Bacteriosis, Infection, Human, Peritoneal dialysis, Prognosis, Pathogen strain, Gram positive bacteria, Gram negative bacteria, Etiology, Epidemiology, Abdominal disease, Extrarenal dialysis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0425378
Code Inist : 002B27B03. Création : 19/12/1997.