Sensitization to Blomia kulagini in a general population of a subtropical region of spain (Canary islands).
The Blomia genus has been described as allergenic in man.
The present study aimed to assess the prevalence of B. kulagini sensitization in a large population of allergic subjects without occupational exposure in a subtropical region (Canary Islands, Spain).
Secondarily, a new standardized B. kulagini extract was evaluated.
The study population comprised 207 patients
RAST for B. kulagini was positive in 76.2% of patients, and 47 of them were selected for the biologic standardization.
When the prick test was performed with the nonstandardized extracts, results were positive in 76.6%, whereas when the test was repeated with the standardized extract, sensitivity rose to 95.7%. The conjunctival provocation test was positive in 78.3% of 46 evaluated patients.
The bronchial provocation test was positive in 18 sensitized patients and negative in five controls.
In conclusion, B
Kulagini is an important cause of sensitization among the occupationally unexposed population of the studied area and should be included in allergy diagnostic tests.
For reliable prick tests, the use of standardized extracts is mandatory.
Mots-clés Pascal : Rhinite, Allergie, Poussière maison, Epidémiologie, Prévalence, Zone subtropicale, Canaries, Iles Atlantiques, Normalisation, Extrait, Allergène, Test provocation, Bronche, Asthme, Conjonctive, Prick test, Test cutané, Homme, ORL pathologie, Nez pathologie, Immunopathologie, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Blomia kulagini, Pneumallergène
Mots-clés Pascal anglais : Rhinitis, Allergy, House dust, Epidemiology, Prevalence, Subtropical zone, Canary Islands, Atlantic Ocean Islands, Standardization, Extract, Allergen, Provocation test, Bronchus, Asthma, Conjunctiva, Prick test, Skin test, Human, ENT disease, Nose disease, Immunopathology, Respiratory disease, Obstructive pulmonary disease, Aeroallergen
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0420652
Code Inist : 002B06C02. Création : 19/12/1997.