An outbreak of Shigella dysenteriae type 2 among laboratory workers due to intentional food contamination.
Context. - Shigella dysenteriae type 2 is rare in the United States, and outbreaks associated with this pathogen are uncommon.
- To determine the magnitude and source of an outbreak of S dysenteriae type 2. Design. - Retrospective cohort.
- Laboratory of a large medical center.
- Case patients were identified as laboratory workers who had diarrhea on or after October 28 and a positive stool culture or temperature greater than 37.8°C. Laboratory workers with diarrhea only were probable case patients.
Main Outcome Measures
- We interviewed laboratory staff and performed identification, serotyping, and pulsed-field get electrophoresis on isolates from case patients, implicated food, and laboratory stock culture.
- From October 29 through November 1, a total of 12 (27%) of 45 laboratory staff developed severe, acute diarrheal illness ; 8 had S dysenteriae isolated from stool and 4 were hospitalized.
All case patients reported having eaten muffins or doughnuts placed in the staff break room on October 29.
Pulsed-field get electrophoresis showed stool isolates from 9 case patients were indistinguishable from S dysenteriae type 2 recovered from an uneaten muffin and from the laboratory's stock strain, a portion of which was missing.
- The source of the outbreak was most likely the laboratory's stock culture, which was used to contaminate the pastries. (...)
Mots-clés Pascal : Shigella dysenteriae, Enterobacteriaceae, Bactérie, Epidémiologie, Rétrospective, Contamination, Etude cohorte, Examen laboratoire, Etiologie, Homme, Appareil digestif pathologie, Bactériose, Infection, Organisation santé
Mots-clés Pascal anglais : Shigella dysenteriae, Enterobacteriaceae, Bacteria, Epidemiology, Retrospective, Contamination, Cohort study, Laboratory investigations, Etiology, Human, Digestive diseases, Bacteriosis, Infection, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0417651
Code Inist : 002B05B02F. Création : 19/12/1997.