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  1. Fulltext. Infant survival, HIV infection, and feeding alternatives in less-developed countries.

    Article - En anglais

    Fulltext.

    Objectives

    This study examines, in the context of the human immunodeficiency virus (HIV) epi-demic, the effects of optimal breast-feeding, complete avoidance of breast-feeding, and early cessation of breast-feeding.

    Methods

    The three categories of breast-feeding were weighed in terms of HIV transmission and infant mortality, Estimates of the frequency of adverse outcomes were obtained by simulation, Results.

    Avoidance of all breast-feeding by the whole population always - produces the worst outcome.

    The lowest frequency of adverse outcomes occurs if no HIV-seroposi-negative women breast-feed optimally, given infant mortality rates below 100 per 1000 and relative risks of dying set at 2.5 for non-breast-fed compared with optimally breast-fed infants.

    For known HIV-seropositive mothers, fewer adverse outcomes result from early cessation than from prolonged breast-feeding if the hazard of HIV transmission through breast-feeding after 3 months is 7% or more, even at high mortality rates, given relative risks of dying set at 1.5 for early cessation compared with optimal duration of breast-feeding.

    Conclusions

    The risk of HIV transmission through breast-feeding at various ages needs to be more precisely quantified.

    The grave issues that may accompany a possible decline in breast-feeding in the less developed world demand evaluation.

    Mots-clés Pascal : Allaitement, Durée, Alimentation, SIDA, Virose, Infection, Nourrisson, Homme, Mortalité, Epidémiologie, Transmission mère enfant, Pays en développement, Modèle simulation, Estimation statistique, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : Breast feeding, Duration, Feeding, AIDS, Viral disease, Infection, Infant, Human, Mortality, Epidemiology, Mother to child transmission, Developing countries, Simulation model, Statistical estimation, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0413219

    Code Inist : 002B30A01A1. Création : 19/12/1997.