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  1. Racial variation in lung cancer.

    Article - En anglais

    Lung cancer claimed about 153 000 lives in 1994 in the United States.

    Despite research overall lung cancer survival has still not improved during the last 20 years, with 5-year relative survival remaining about 13% (1).

    In addition several epidemiologic and molecular studies showed a difference in the incidence of lung cancer in the three major races.

    The aim of our study was to investigate the variations of race in lung cancer patients, in order to identify potential risk factors linked to the different racial status.

    In this light we compared a 10 years lung cancer data of black population from Howard University Hospital, Washington D.C., U.S.A. and a 20 years data of white population from the Vienna University Hospital, Austria.

    Our results did not show any significant difference in mean age or tumor localization in both groups, but highlighted a remarkable difference in the incidence of the lung cancer histological types also according to the sex.

    In this respect it could be more successful to consider carcinogenesis like a protracted process of gene function deregulation in response to cell injury from exposure to genotoxic substances with individual specificity.

    Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Facteur risque, Race, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Autriche, Europe, Homme, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie

    Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Risk factor, Race, Epidemiology, United States, North America, America, Austria, Europe, Human, Respiratory disease, Lung disease, Bronchus disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0413150

    Code Inist : 002B11A. Création : 19/12/1997.