International differences in epidemiology of lung adenocarcinoma.
Copyright (c) 1997 Elsevier Science Ireland Ltd.
All rights reserved.
In Europe, the squamous cell carcinoma is the most frequent non-small cell lung cancer (NSCLC) subtype and until now, no increase in incidence of lung adenocarcinoma (ADC) has been described (except in the Netherlands), in contrast to North America where ADC predominates.
Our aim was to compare the percentage of ADC in Montreal (MTL), Canada, with that in Strasbourg (STBG), France.
We prospectively identified patients with NSCLC in MTL and in STBG over an 8-month period and described the distribution of NSCLC by sex, age, subtype and smoking history.
A total of 172 patients in MTL and 166 in STBG were identified.
The male/female ratio was significantly different in STBG (12 : 1) and in MTL (2 : 1).
The percentage of ADC was significantly higher in MTL (40%) than in STBG (30%). This difference is partly due to the higher number of women with NSCLC in Montreal combined with the predominance of ADC in women.
The proportion of ADC decreased with age in STBG, but was similar in each age category in MTL.
In STBG, most women with NSCLC had never smoked (69%), in contrast to MTL where only 16% of women had never smoked.
In conclusion, ADC is more frequent in MTL than in STBG.
This is partly due to the higher number of women with NSCLC in MTL combined with the predominance of ADC in women. (...)
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Adénocarcinome, Epidémiologie, Homme, Europe, Tabagisme, Facteur risque, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Adenocarcinoma, Epidemiology, Human, Europe, Tobacco smoking, Risk factor, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0412291
Code Inist : 002B11A. Création : 19/12/1997.