To locate sources of occupational exposure to nasal and bladder carcinogens for surveillance follow up in British Columbia, Canada.
Methods-Incident cases of nasal cancer (n=48), bladder cancer (n=105), and population based controls (n=159) matched for sex and age, were interviewed about their jobs, exposures, and smoking histories.
Odds ratios (ORs) were calculated for 57 occupational groups with stratified exact methods to control for age, sex, and smoking.
--Occupational groups at increased risk of nasal cancer included :
textile workers (six cases, OR 7.6) ;
miners, drillers, and blasters (six cases, OR 3.5) ;
welders (two cases, OR 3.5) ;
pulp and paper workers (three cases, OR 3.1) ;
and plumbers and pipefitters (two cases, OR 3.0).
Nasal cancer ORs were not increased in occupations exposed to wood dust, possibly due to low exposures in local wood industries.
Strongly increased risks of bladder cancer were found for sheet metal workers (four cases, OR 5.3), miners (19 cases, OR 4.5), gardeners (six cases, OR 3.7), and hairdressers (three cases, OR 3.2).
Among occupations originally considered at risk, the following had increased risks of bladder cancer :
painters (four cases, OR 2.8) ;
laundry workers (five cases, OR 2.3) ;
chemical and petroleum workers (15 cases, OR 1.8) ;
machinists (eight cases, OR 1.6) ;
and textile workers (three cases, OR 1.5). (...)
Mots-clés Pascal : Carcinogène, Source pollution, Exposition professionnelle, Tumeur maligne, Nez, Vessie urinaire, Médecine travail, Industrie, Surveillance biologique, Colombie britannique, Canada, Amérique du Nord, Amérique, Homme, Epidémiologie, ORL pathologie, Nez pathologie, Appareil urinaire pathologie, Voie urinaire pathologie, Vessie pathologie
Mots-clés Pascal anglais : Carcinogen, Pollution source, Occupational exposure, Malignant tumor, Nose, Urinary bladder, Occupational medicine, Industry, Biological monitoring, British Columbia, Canada, North America, America, Human, Epidemiology, ENT disease, Nose disease, Urinary system disease, Urinary tract disease, Bladder disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0411757
Code Inist : 002B10B01. Création : 19/12/1997.