logo BDSP

Base documentaire


Votre avis nous intéresse

Le réseau BDSP met en oeuvre un projet d'innovation et d'amélioration de ses services, dans le souci constant de proposer des contenus de qualité adaptés aux besoins des utilisateurs.

Identifier de nouvelles sources de financements est la condition nécessaire pour assurer la poursuite et la pérennité de cet outil unique qu'est la BDSP, tout en le faisant évoluer.

Pour définir un nouveau modèle économique, nous avons besoin de votre avis : merci de répondre à notre enquête (temps estimé : 5 minutes).

Participer maintenant
Participer plus tard J'ai déjà participé

  1. Evaluation of febrile infants under 3 months of age : Is routine lumbar puncture warranted ?

    Article - En anglais

    Fever may be the sole clinically evident presentation of serious bacterial infection (SBI) in a very young infant, and therefore lumbar puncture is still widely regarded as a mandatory procedure in the sepsis workup of febrile infants under 2 months of age.

    In this retrospective study, we evaluated the frequency and the diagnostic value of cerebrospinal fluid examination in 492 infants aged less than 3 months who were hospitalized because of fever during 1988-1994.

    The patients were categorized as being at « high risk » or « low risk » for SBI according to current clinical and laboratory criteria.

    Among the 492 infants, 196 (40%) were identified as « high-risk » for SBI, and 296 (60%) were at low risk.

    Among the overall series of infants, 60 babies (12%) were subsequently proven with bacterial infection.

    Among the 196 « high-risk » babies, 26% had bacterial infection, compared to only 3% of the 296 infants at low risk (p<0.0001), denoting a sensitivity of 85% and a specificity of 65% of the clinical classification criteria.

    Lumbar puncture was done to 186 (46%) infants upon hospital admission ; 176 punctures yielded satisfactory samples of cerebrospinal fluid (CSF).

    Sixteen (3%) patients had abnormal CSF findings :

    2 of them had positive bacterial cultures and 14 were compatible with aseptic meningitis.

    The 2 patients with purulent meningitis were clinically very ill and were immediately recognized as deserving a lumbar puncture. (...)

    Mots-clés Pascal : Fièvre, Epidémiologie, Nouveau né, Homme, Etiologie, Diagnostic, Evaluation, Ponction aspiration, Lombaire, Israël, Asie, Infection

    Mots-clés Pascal anglais : Fever, Epidemiology, Newborn, Human, Etiology, Diagnosis, Evaluation, Aspiration punction, Lumbar, Israel, Asia, Infection

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0398239

    Code Inist : 002B05A01. Création : 12/09/1997.