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  1. Outbreak of toxoplasmosis associated with municipal drinking water.

    Article - En anglais

    Background Outbreaks of toxoplasmosis are recognised infrequently.

    In March, 1995, a sudden increase of serologically diagnosed cases of acute toxoplasmosis was noted in the Greater Victoria area of British Columbia, Canada.

    Concurrently, but independently, seven cases of acute toxoplasma retinitis were diagnosed against a background of no cases in the previous 5 years.

    Methods Cases were defined by serological testing, clinical presentation, and residence in Greater Victoria.

    A screening programme for women who were or had been pregnant was started.

    Geographical mapping of cases, and case-control studies of symptomatic cases and of women enrolled in the screening programme were done.

    Findings 100 individuals aged 6 to 83 years met the definition for an acute, outbreak-related case. 94 resided in Greater Victoria and six had visited it ; 19 had retinitis, 51 had lymphadenopathy, four others had symptoms consistent with toxoplasmosis, seven had other symptoms, 18 were symptom-free, and one would not provide information. 36 (0.9%) of 3812 screened pregnant and postnatal women were cases.

    Excess cases were not detected outside Greater Victoria and no conventional source of toxoplasmosis was implicated.

    Mapping studies of cases and of the screened women, and both case-control studies showed significant associations between acute infection and residence in the distribution system of one reservoir supplying water to Greater Victoria (ORs or RRs : 3.53,3.05,8.27, and 5. (...)

    Mots-clés Pascal : Toxoplasmose, Protozoose, Parasitose, Infection, Incidence, Association, Eau potable, Echelon municipal, Facteur risque, Complication, Répartition géographique, Contamination, Homme, Canada, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Toxoplasmosis, Protozoal disease, Parasitosis, Infection, Incidence, Association, Drinking water, Municipal scope, Risk factor, Complication, Geographic distribution, Contamination, Human, Canada, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0397969

    Code Inist : 002B05E02B5. Création : 12/09/1997.