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  1. Health-related quality of life after epilepsy surgery : A Swedish multicenter study.

    Article - En anglais


    To investigate health-related quality of life (HRQOL) in relation to seizure outcome as part of a multicenter follow-up of epilepsy surgery in Sweden.


    A battery including the SF-36 Health Survey and the Hospital Anxiety and Depression scale (HAD) was distributed to all patients older than 16 years.

    Mean follow-up time was 4 years (range, 2-13 years) and response rate, 91% (103 of 113 patients).

    HRQOL data were related to seizure frequency and severity (Chalfont Seizure Severity Scale).


    Seventy-six percent considered their global health to be better than it was before surgery.

    Degree of improvement in seizure control correlated with improved satisfaction with health (Spearman's r=0.44).

    Higher SF-36 scores (higher HRQOL ratings) correlated with percentage reduction of seizure frequency for all scales and was strongest for perception of general health (Spearman's r=0.46).

    When the patients were divided into four categories [A. completely seizure free (n=29) ; B, seizure free with aura (n=18) ; C, =75% reduction in seizure frequency (n=24) ; and D,<75% reduction in seizure frequency (n=32) ], a strong positive association was found between higher SF-36 scores (with the exception of physical functioning) and better seizure control.

    Health-related limitations in role performance differentiated best between the outcome categories. (...)

    Mots-clés Pascal : Epilepsie, Réfractaire, Qualité vie, Santé, Etude multicentrique, Suède, Europe, Traitement, Chirurgie, Evolution, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie

    Mots-clés Pascal anglais : Epilepsy, Refractory, Quality of life, Health, Multicenter study, Sweden, Europe, Treatment, Surgery, Evolution, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0396001

    Code Inist : 002B25J01. Création : 12/09/1997.