To investigate health-related quality of life (HRQOL) in relation to seizure outcome as part of a multicenter follow-up of epilepsy surgery in Sweden.
A battery including the SF-36 Health Survey and the Hospital Anxiety and Depression scale (HAD) was distributed to all patients older than 16 years.
Mean follow-up time was 4 years (range, 2-13 years) and response rate, 91% (103 of 113 patients).
HRQOL data were related to seizure frequency and severity (Chalfont Seizure Severity Scale).
Seventy-six percent considered their global health to be better than it was before surgery.
Degree of improvement in seizure control correlated with improved satisfaction with health (Spearman's r=0.44).
Higher SF-36 scores (higher HRQOL ratings) correlated with percentage reduction of seizure frequency for all scales and was strongest for perception of general health (Spearman's r=0.46).
When the patients were divided into four categories [A. completely seizure free (n=29) ; B, seizure free with aura (n=18) ; C, =75% reduction in seizure frequency (n=24) ; and D,<75% reduction in seizure frequency (n=32) ], a strong positive association was found between higher SF-36 scores (with the exception of physical functioning) and better seizure control.
Health-related limitations in role performance differentiated best between the outcome categories. (...)
Mots-clés Pascal : Epilepsie, Réfractaire, Qualité vie, Santé, Etude multicentrique, Suède, Europe, Traitement, Chirurgie, Evolution, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie
Mots-clés Pascal anglais : Epilepsy, Refractory, Quality of life, Health, Multicenter study, Sweden, Europe, Treatment, Surgery, Evolution, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0396001
Code Inist : 002B25J01. Création : 12/09/1997.