This study investigates the clinical features of chronic calcifying pancreatitis (CCP) in Taiwan and also the comparative differences in the disorder as it affects orientals and occidentals.
Medical records at seven tertiary hospitals relating to patients diagnosed with CCP between 1976 and 1996 are reviewed and analyzed.
Defining the calcification of the pancreas is achieved by plain film, ultrasonography, computed tomography, or histology.
CCP afflicts men more frequently than it does women, by a ratio of 3.5 : 1 (70 men and 20 women).
The mean age is 45 years (male : 46 female : 41.4).
For fifty-two patients (57.8%), alcohol is the major cause of the condition, while in others, the causes are non-alcoholic (idiopathic : 31 ; biliary : 4 ; hereditary : 3).
Alcoholism is mainly associated with males and younger sufferers.
The major complications are diabetes mellitus (53.3%), cysts or pseudocysts (21.1%), and biliary stricture or stones (20%). Pancreatic adenocarcinoma and splenic vein thrombosis were found in six and five patients, respectively.
Three patients died from cancers of other than pancreatic origin (lung : 1 ; liver : 1 ; bile duct : 1).
Thirty-three patients were treated surgically of which thirteen (39.4%), including one with pancreatic auto transplantation, improved.
Fifty-seven patients received medical treatment but only eleven (19.3%) improved. (...)
Mots-clés Pascal : Pancréatite, Complication, Calcification, Symptomatologie, Effet biologique, Origine ethnique, Etude comparative, Etude statistique, Homme, Japon, Asie, Appareil digestif pathologie, Pancréas pathologie
Mots-clés Pascal anglais : Pancreatitis, Complication, Calcification, Symptomatology, Biological effect, Ethnic origin, Comparative study, Statistical study, Human, Japan, Asia, Digestive diseases, Pancreatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0395729
Code Inist : 002B13C03. Création : 12/09/1997.