Science Writer's Seminar of the American Cancer Society. San Francisco, California (USA), 1996/03/26.
Characteristics that determine the anatomic site within the colorectum where carcinoma is most likely to occur would be useful in choosing optimal modalities for cancer screening and in the study of etiology.
The aim of this study was to identify any association of gender, race, or age with colorectal carcinoma in the proximal or distal colorectum.
A descriptive, population-based epidemiologic study was conducted on colorectal carcinoma (CRC) cases identified through the Illinois Tumor Registry.
Among CRC patients diagnosed between 1986 and 1991, age at diagnosis (40-90 years), gender, white or African American race, and subsite of CRC location were identified.
Incidence rates were determined with demographic data from the 1990 Illinois census.
Logistic regression was used to identify significant subsite specific risk factors for CRC.
During the study period, 38,931 cases of CRC occurred in Illinois among whites and African Americans between the ages of 40 and 90 years.
Age, race, and gender were independently significantly associated with both proximal and distal CRC risk (P<0.0001).
The greatest risk for white males was for distal CRC, followed by the risk for African American males of developing CRC in the distal colorectum.
African Americans were more likely than whites to develop proximal CRC (odds ratio [OR]=1.19), whereas whites were more likely to have distal CRC than African Americans (OR=1.26). (...)
Mots-clés Pascal : Carcinome, Côlon, Rectum, Distribution, Age, Race, Sexe, Facteur risque, Epidémiologie, Illinois, Etats Unis, Amérique du Nord, Amérique, Registre, Régression logistique, Analyse statistique, Homme, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie
Mots-clés Pascal anglais : Carcinoma, Colon, Rectum, Distribution, Age, Race, Sex, Risk factor, Epidemiology, Illinois, United States, North America, America, Register, Logistic regression, Statistical analysis, Human, Malignant tumor, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0393440
Code Inist : 002B13B01. Création : 12/09/1997.