Context. - Sepsis syndrome is a leading cause of mortality in hospitalized patients.
However, few studies have described the epidemiology of sepsis syndrome in a hospitalwide population.
- To describe the epidemiology of sepsis syndrome in the tertiary care hospital setting.
- Prospective, multi-institutional, observational study including 5-month follow-up.
- Eight academic tertiary care centers.
- Each center monitored a weighted random sample of intensive care unit (ICU) patients, non-ICU patients who had blood cultures drawn, and all patients who received a novel therapeutic agent or who died in an emergency department or ICU.
Sepsis syndrome was defined as the presence of either a positive blood culture or the combination of fever, tachypnea, tachycardia, clinically suspected infection, and any 1 of 7 confirmatory criteria.
Estimates of total cases expected annually were extrapolated from the number of cases, the period of observation, and the sampling fraction.
- From January 4,1993, to April 2,1994,12 759 patients were monitored and 1342 episodes of sepsis syndrome were documented.
The extrapolated, weighted estimate of hospitalwide incidence (mean ±95% confidence limit) of sepsis syndrome was 2.0±0.16 cases per 100 admissions, or 2.8±0.17 per 1000 patient-days. (...)
Mots-clés Pascal : Septique syndrome, Infection, Epidémiologie, Prospective, Centre santé, Tertiaire, Facteur prédictif, Traitement, Coût, Homme, Organisation santé
Mots-clés Pascal anglais : Sepsis syndrome, Infection, Epidemiology, Prospective, Health center, Tertiary, Predictive factor, Treatment, Costs, Human, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0388376
Code Inist : 002B05A01. Création : 12/09/1997.