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  1. Epidemiology of sepsis syndrome in 8 academic medical centers.

    Article - En anglais

    Context. - Sepsis syndrome is a leading cause of mortality in hospitalized patients.

    However, few studies have described the epidemiology of sepsis syndrome in a hospitalwide population.


    - To describe the epidemiology of sepsis syndrome in the tertiary care hospital setting.


    - Prospective, multi-institutional, observational study including 5-month follow-up.


    - Eight academic tertiary care centers.


    - Each center monitored a weighted random sample of intensive care unit (ICU) patients, non-ICU patients who had blood cultures drawn, and all patients who received a novel therapeutic agent or who died in an emergency department or ICU.

    Sepsis syndrome was defined as the presence of either a positive blood culture or the combination of fever, tachypnea, tachycardia, clinically suspected infection, and any 1 of 7 confirmatory criteria.

    Estimates of total cases expected annually were extrapolated from the number of cases, the period of observation, and the sampling fraction.


    - From January 4,1993, to April 2,1994,12 759 patients were monitored and 1342 episodes of sepsis syndrome were documented.

    The extrapolated, weighted estimate of hospitalwide incidence (mean ±95% confidence limit) of sepsis syndrome was 2.0±0.16 cases per 100 admissions, or 2.8±0.17 per 1000 patient-days. (...)

    Mots-clés Pascal : Septique syndrome, Infection, Epidémiologie, Prospective, Centre santé, Tertiaire, Facteur prédictif, Traitement, Coût, Homme, Organisation santé

    Mots-clés Pascal anglais : Sepsis syndrome, Infection, Epidemiology, Prospective, Health center, Tertiary, Predictive factor, Treatment, Costs, Human, Public health organization

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0388376

    Code Inist : 002B05A01. Création : 12/09/1997.