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  1. Airborne (1-3) - bêta-D-glucan and airway disease in a day-care center before and after renovation.

    Article - En anglais

    Changes in symptoms and airway responsiveness among persons who worked in a day-care center that had microbial growth problems were assessed before and after renovation.

    Before and after the building renovation, the investigators used the Limulus assay with (1-3) - bêta-D-glucan-specific lysate to measure airborne levels of (1-3) - bêta-D-glucan, a cell-wall component of molds.

    Airway responsiveness and subjective symptoms were measured among 14 female employees with a methacholine test and a standardized questionnaire.

    After the renovation, (1-3) - bêta-D-glucan-glucan levels decreased from 11.4 to 1.4 ng/m3.

    The number of persons who had increased airway responsiveness decreased after the renovation.

    Two employees developed a classical allergy to cat and pollen during the observation period.

    Although the study included only a few subjects and was based on only one day-care center, the data suggest that (1-3) - bêta-D-glucan may be related to airways inflammation caused by indoor air pollution.

    Mots-clés Pascal : Humidité, Moisissure, Teneur air ambiant, Pollution intérieur, Rénovation, Bâtiment, Garderie enfant, Suède, Europe, Voie respiratoire, Fonction respiratoire, Homme, Personnel sanitaire, Exposition professionnelle, Médecine travail, Appareil respiratoire pathologie, 1,3-bêta-Glucane

    Mots-clés Pascal anglais : Humidity, Mould, Ambient air concentration, Indoor pollution, Renovation, Buildings, Day care center, Sweden, Europe, Respiratory tract, Lung function, Human, Health staff, Occupational exposure, Occupational medicine, Respiratory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0387280

    Code Inist : 002A05D05. Création : 12/09/1997.