Changes in symptoms and airway responsiveness among persons who worked in a day-care center that had microbial growth problems were assessed before and after renovation.
Before and after the building renovation, the investigators used the Limulus assay with (1-3) - bêta-D-glucan-specific lysate to measure airborne levels of (1-3) - bêta-D-glucan, a cell-wall component of molds.
Airway responsiveness and subjective symptoms were measured among 14 female employees with a methacholine test and a standardized questionnaire.
After the renovation, (1-3) - bêta-D-glucan-glucan levels decreased from 11.4 to 1.4 ng/m3.
The number of persons who had increased airway responsiveness decreased after the renovation.
Two employees developed a classical allergy to cat and pollen during the observation period.
Although the study included only a few subjects and was based on only one day-care center, the data suggest that (1-3) - bêta-D-glucan may be related to airways inflammation caused by indoor air pollution.
Mots-clés Pascal : Humidité, Moisissure, Teneur air ambiant, Pollution intérieur, Rénovation, Bâtiment, Garderie enfant, Suède, Europe, Voie respiratoire, Fonction respiratoire, Homme, Personnel sanitaire, Exposition professionnelle, Médecine travail, Appareil respiratoire pathologie, 1,3-bêta-Glucane
Mots-clés Pascal anglais : Humidity, Mould, Ambient air concentration, Indoor pollution, Renovation, Buildings, Day care center, Sweden, Europe, Respiratory tract, Lung function, Human, Health staff, Occupational exposure, Occupational medicine, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0387280
Code Inist : 002A05D05. Création : 12/09/1997.