Context. - The generalizability of currently available estimates of survival after radical prostatectomy is theoretically limited.
To obtain generalizable estimates of survival after radical prostatectomy.
- A population-based retrospective cohort study.
- Nine regions of the United States.
- Patients who were diagnosed with prostate cancer between 1983 and 1987 and underwent radical prostatectomy and lymph node dissection.
- Proportional hazards models incorporating geographical region, age, race, pathological stage, lymph node involvement, and tumor grade to identify independent correlates of disease-specific and overall survival and life table analyses to estimate 10-year survival distributions.
- A total of 3626 patients with a mean age of 65 years were included in the study ; 92.6% were white, 54.2% had moderate-grade cancer, 60.4% had no extension beyond the prostate, and 91.2% had no lymph node involvement.
Using San Francisco-Oakland, Calif, as a reference region, no other region was significantly associated with a risk of disease-specific or overall mortality.
Older age and black race were independently associated with worse overall but not disease-specific survival.
Higher grade, extension beyond the prostate, and lymph node involvement were independently associated with worse disease-specific and overall survival. (...)
Mots-clés Pascal : Prostatectomie, Exérèse élargie, Rétrospective, Survie, Etude cohorte, Etats Unis, Amérique du Nord, Amérique, Evaluation, Homme, Campagne de masse, Chirurgie, Appareil génital mâle pathologie, Prostate, Organisation santé
Mots-clés Pascal anglais : Prostatectomy, Radical resection, Retrospective, Survival, Cohort study, United States, North America, America, Evaluation, Human, Mass campaign, Surgery, Male genital diseases, Prostate, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0381074
Code Inist : 002B25H. Création : 12/09/1997.