Residential exposure to magnetic fields and acute lymphoblastic leukemia in children.
Background Previous studies found associations between childhood leukemia and surrogate indicators of exposure to magnetic fields (the power-line classification scheme known as « wire coding »), but not between childhood leukemia and measurements of 60-Hz residential magnetic fields.
Methods We enrolled 638 children with acute lymphoblastic leukemia (ALL) who were under 15 years of age and were registered with the Children's Cancer Group and 620 controls in a study of residential exposure to magnetic fields generated by nearby power lines.
In the subjects'current and former homes, data collectors blinded to the subjects'health status measured magnetic fields for 24 hours in each child's bedroom and for 30 seconds in three or four other rooms and outside the front door.
A computer algorithm assigned wire-code categories, based on the distance and configuration of nearby power lines, to the subjects'main residences (for 416 case patients and 416 controls) and to those where the family had lived during the mother's pregnancy with the subject (for 230 case patients and 230 controls).
Results The risk of childhood ALL was not linked to summary time-weighted average residential magnetic-field levels, categorized according to a priori criteria.
The odds ratio for ALL was 1.24 (95 percent confidence interval, 0.86 to 1.79) at exposures of 0.200 pT or greater as compared with less than 0.065 muT. (...)
Mots-clés Pascal : Leucémie lymphoblastique, Relation incertitude, Facteur risque, Environnement physique, Ligne électrique, Champ magnétique, Etude comparative, Enfant, Homme, Aigu, Hémopathie maligne, Lymphoprolifératif syndrome
Mots-clés Pascal anglais : Acute lymphocytic leukemia, Uncertainty relation, Risk factor, Physical environment, Power transmission line, Magnetic field, Comparative study, Child, Human, Acute, Malignant hemopathy, Lymphoproliferative syndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0370049
Code Inist : 002B19B. Création : 12/09/1997.