To determine the demographic, environmental, and medical factors that influence the relative weights of the newborn infant and the placenta and compare this ratio with other factors known to predispose to adult ill health.
Prospective cohort study.
The tertiary referral centre for perinatal care in Perth, Western Australia Subjects : 2507 pregnant women who delivered a single live infant at term.
Placental weight, birth weight and the ratio of placental weight to birth weight.
By multiple regression analysis the placental weight to birthweight ratio was significantly and positively associated with gestational age, female sex, Asian parentage, increasing maternal body mass index, increased maternal weight at booking, lower socioeconomic status, maternal anaemia, and increasing number of cigarettes smoked daily.
There were no consistent relations between the placental weight to birthweight ratio and measures of newborn size.
The ratio of placental weight to birth weight is not an accurate marker of fetal growth.
In its role as a predictor of adult disease the ratio may be acting as a surrogate for other factors which are already known to influence health and may act before or after birth. (...)
Mots-clés Pascal : Poids naissance, Nouveau né, Homme, Association, Placenta, Etude cohorte, Facteur prédictif, Epidémiologie, Incidence, Maladie, Relation mère foetus, Appareil génital femelle pathologie, Pédiatrie
Mots-clés Pascal anglais : Birth weight, Newborn, Human, Association, Placenta, Cohort study, Predictive factor, Epidemiology, Incidence, Disease, Fetomaternal relation, Female genital diseases, Pediatrics
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0369988
Code Inist : 002B20F02. Création : 12/09/1997.