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  1. Prospective study of effect of switching from cigarettes to pipes or cigars on mortality from three smoking related diseases.

    Article - En anglais

    Objective 

    To estimate the extent to which cigarette smokers who switch to cigars or pipes alter their risk of dying of three smoking related diseases-lung cancer, ischaemic heart disease, and chronic obstructive lung disease.

    Design 

    A prospective study of 21 520 men aged 35-64 years when recruited in 1975-82 with detailed history of smoking and measurement of carboxyhaemoglobin.

    Main outcome measures 

    Notification of deaths (to 1993) classified by cause.

    Results 

    Pipe and cigar smokers who had switched from cigarettes over 20 years before entry to the study smoked less tobacco than cigarette smokers (8.1 g/day v 20 g/day), but they had the same consumption as pipe and cigar smokers who had never smoked cigarettes (8.1 g) and had higher carboxyhaemoglobin saturations (1.2% v 1.0%, P<0.001), indicating that they inhaled tobacco smoke to a greater extent.

    They had a 51% higher risk of dying of the three smoking related diseases than pipe or cigar smokers who had never smoked cigarettes (relative risk 1.51 ; 95% confidence interval 0.96 to 2.38), a 68% higher risk than lifelong non-smokers (1.68 ; 1.16 to 2.45), a 57% higher risk than former cigarette smokers who gave up smoking over 20 years before entry (1.57 ; 1.04 to 2.38), and a 46% lower risk than continuing cigarette smokers (0.54 ; 0.38 to 0.77).

    Conclusion 

    Cigarette smokers who have difficulty in giving up smoking altogether are better off changing to cigars or pipes than continuing to smoke cigarettes. (...)

    Mots-clés Pascal : Tabagisme, Prospective, Facteur risque, Commutation, Cigare, Evaluation, Inhalation, Fumée, Mortalité, Carboxyhémoglobine, Homme, Toxicologie, Appareil respiratoire pathologie, Politique sanitaire, Activité biologique

    Mots-clés Pascal anglais : Tobacco smoking, Prospective, Risk factor, Switching, Cigar, Evaluation, Inhalation, Fumes, Mortality, Carboxyhemoglobin, Human, Toxicology, Respiratory disease, Health policy, Biological activity

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0369987

    Code Inist : 002B03E. Création : 12/09/1997.