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  1. Acute pancreatitis in Sowetan Africans : A disease with high mortality and morbidity.

    Article, Communication - En anglais

    South African Gastroenterology Society. Sun City (ZAF), 1995/09/12.


    In African blacks, acute pancreatitis requiring hospital admission is a severe disease associated with a high mortality and significant long-term morbidity in surviving patients.


    It has been suggested that acute pancreatitis has a benign course in Africans in contrast to Western populations.

    The aim of the present study was to ascertain the incidence of acute pancreatitis at Baragwanath Hospital for a 1-yr period and to test the validity of the above hypothesis.


    One hundred thirty-six patients with acute pancreatitis were retrospectively assessed.

    Fifty patients were available for a prospective follow-up examination and underwent sonographic and biochemical investigations.

    Acute pancreatitis was diagnosed if the patient presented with the typical clinical picture and a raised serum amylase level>800 U/L. Results.

    The study consisted of 108 male and 28 female patients.

    Alcohol was identified as the predominant etiologic factor in 83.1%, biliary disease in 7.4%, and idiopathic causes in 6.6%. Substantial morbidity was encountered in 32.3% and was caused mainly by pancreatic complications, metabolic derangements, alcoholrelated symptoms, and respiratory impairment.

    A portion (10.3%) ofthe patients developed further pancreatic pathology, such as pseudocysts, necroses, or an abscess.

    The overall mortality rate was 8.1%. Patients who died had a higher mean serum amylase, and most deaths occurred within 2 d of admission. (...)

    Mots-clés Pascal : Pancréatite, Aigu, Incidence, Facteur risque, Complication, Mortalité, Morbidité, Long terme, Etude statistique, Homme, République Sud Africaine, Afrique, Appareil digestif pathologie, Pancréas pathologie

    Mots-clés Pascal anglais : Pancreatitis, Acute, Incidence, Risk factor, Complication, Mortality, Morbidity, Long term, Statistical study, Human, South Africa, Africa, Digestive diseases, Pancreatic disease

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    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0369802

    Code Inist : 002B13B03. Création : 12/09/1997.