Acute pancreatitis in Sowetan Africans : A disease with high mortality and morbidity.
South African Gastroenterology Society. Sun City (ZAF), 1995/09/12.
In African blacks, acute pancreatitis requiring hospital admission is a severe disease associated with a high mortality and significant long-term morbidity in surviving patients.
It has been suggested that acute pancreatitis has a benign course in Africans in contrast to Western populations.
The aim of the present study was to ascertain the incidence of acute pancreatitis at Baragwanath Hospital for a 1-yr period and to test the validity of the above hypothesis.
One hundred thirty-six patients with acute pancreatitis were retrospectively assessed.
Fifty patients were available for a prospective follow-up examination and underwent sonographic and biochemical investigations.
Acute pancreatitis was diagnosed if the patient presented with the typical clinical picture and a raised serum amylase level>800 U/L. Results.
The study consisted of 108 male and 28 female patients.
Alcohol was identified as the predominant etiologic factor in 83.1%, biliary disease in 7.4%, and idiopathic causes in 6.6%. Substantial morbidity was encountered in 32.3% and was caused mainly by pancreatic complications, metabolic derangements, alcoholrelated symptoms, and respiratory impairment.
A portion (10.3%) ofthe patients developed further pancreatic pathology, such as pseudocysts, necroses, or an abscess.
The overall mortality rate was 8.1%. Patients who died had a higher mean serum amylase, and most deaths occurred within 2 d of admission. (...)
Mots-clés Pascal : Pancréatite, Aigu, Incidence, Facteur risque, Complication, Mortalité, Morbidité, Long terme, Etude statistique, Homme, République Sud Africaine, Afrique, Appareil digestif pathologie, Pancréas pathologie
Mots-clés Pascal anglais : Pancreatitis, Acute, Incidence, Risk factor, Complication, Mortality, Morbidity, Long term, Statistical study, Human, South Africa, Africa, Digestive diseases, Pancreatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0369802
Code Inist : 002B13B03. Création : 12/09/1997.