Will early detection impact on stage of disease and recurrence of prostate cancer in a high risk population ?
We initiated a community based study to educate and recruit African American men for early diagnosis of prostate cancer, that is the Detroit Education and Early Detection (DEED) study.
Our objective was to evaluate our recruitment process for this target population, examine the percentage of organ confined prostate cancer in men undergoing radical prostatectomy and measure recurrence biochemically.
A community based study from February 1993 to February 1995 through the African American churches in metropolitan Detroit was initiated.
We compared the early detection group treated with radical prostatectomy to the population presenting to our urological clinic during the same period.
We tested and followed 1,105 African American men using the prostate specific antigen blood test.
Pathologically organ confined prostate cancer was diagnosed in 11 of 17 men (65%) who underwent radical prostatectomy in the DEED project.
Within the clinic population 35% of the African American men were diagnosed with pathologically organ confined prostate cancer.
The difference between the 2 populations was statistically significant (p=0.033).
Disease recurred in 1 of 15 (7%) and 39 of 157 (25%) men in the DEED and clinic populations, respectively (p=0.97). (...)
Mots-clés Pascal : Adénocarcinome, Prostate, Dépistage, Education santé, Etats Unis, Amérique du Nord, Amérique, Exploration, Survie, Adulte, Homme, Mâle, Négroïde, Tumeur maligne, Appareil urinaire pathologie, Appareil génital mâle pathologie, Prostate pathologie
Mots-clés Pascal anglais : Adenocarcinoma, Prostate, Medical screening, Health education, United States, North America, America, Exploration, Survival, Adult, Human, Male, Negroid, Malignant tumor, Urinary system disease, Male genital diseases, Prostate disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0368744
Code Inist : 002B14D02. Création : 12/09/1997.