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  1. Lipids in serum of patients with malignant ovarian neoplasms.

    Article - En anglais

    Objective 

    In numerous papers, different associations of serum lipids and lipoproteins with neoplastic diseases were found.

    The aim of our work was to find out associations between levels of 11 serum lipids, lipoproteins and ovarian cancer.

    Methods 

    25 healthy women and 25 patients with ovarian cancer underwent examinations.

    Uni-and multivariate analysis of variance and discrimination analysis were used to analyze our results.

    Results 

    The analysis demonstrates that ovarian carcinoma is associated with a significant reduction of total cholesterol and its esters in serum and in high density lipoprotein fractions compared to controls.

    Conclusion 

    It could be shown that using multivariate analysis of variance it is possible to find the optimal set of serum lipid parameters, containing serum esterified cholesterol, serum total cholesterol and high density lipoproteins esterified cholesterol, to differentiate healthy persons from patients affected by ovarian cancer.

    Mots-clés Pascal : Carcinome, Ovaire, Association, Hyperlipoprotéinémie, Dépistage, Analyse multivariable, Analyse assistée, Infographie, Diagnostic, Evaluation, Pronostic, Homme, Femelle, Lipide, Tumeur maligne, Appareil génital femelle pathologie, Ovaire pathologie, Métabolisme pathologie, Dyslipémie, Technologie, Organisation santé

    Mots-clés Pascal anglais : Carcinoma, Ovary, Association, Hyperlipoproteinemia, Medical screening, Multivariate analysis, Computer aided analysis, Computer graphics, Diagnosis, Evaluation, Prognosis, Human, Female, Lipids, Malignant tumor, Female genital diseases, Ovarian diseases, Metabolic diseases, Dyslipemia, Technology, Public health organization

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0361240

    Code Inist : 002B20C02. Création : 12/09/1997.