To determine the risk of all cause mortality and the incidence of major coronary heart disease (CHD) events in lifelong teetotallers and in ex-drinkers compared with occasional and regular drinkers.
A prospective study of middle-aged men drawn at random from one general practice in each of 24 British towns.
Five years after the screening of 7735 men aged 40-59 years, 7167 provided further information on postal questionnaire enabling separation of non-drinkers into lifelong teetotallers and ex-drinkers.
During the follow-up period of 9.8 years after the postal questionnaire there were 929 deaths from all causes and 490 major CHD events.
Ex-drinkers exhibited increased cardiovascular and non-cardiovascular mortality ; lifelong teetotallers showed the lowest cardiovascular mortality but a significantly increased non-cardiovascular mortality.
After adjustment for confounding factors and pre-existing disease, the two non-drinking groups did not differ significantly in all cause mortality from occasional and regular drinkers (light, moderate or heavy) but lifelong teetotallers still showed a significant increase in non-cardiovascular mortality.
Adjustment considerably attenuated the risk of both cardiovascular and non-cardiovascular mortality in the ex-drinkers. (...)
Mots-clés Pascal : Consommation, Boisson alcoolisée, Abstinence, Ancien buveur, Cardiopathie coronaire, Mortalité, Epidémiologie, Incidence, Facteur risque, Homme, Mâle, Royaume Uni, Europe, Etude comparative, Appareil circulatoire pathologie
Mots-clés Pascal anglais : Consumption, Alcoholic beverage, Abstinence, Former alcoholic, Coronary heart disease, Mortality, Epidemiology, Incidence, Risk factor, Human, Male, United Kingdom, Europe, Comparative study, Cardiovascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0350703
Code Inist : 002B12A03. Création : 12/09/1997.