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  1. The impact of immunization control activities on measles outbreaks in middle and low income countries.

    Article - En anglais

    Background

    The World Health Organization recommended strategy for responding to measles outbreaks in developing countries does not promote the use of immunization campaigns due to their high cost, disruptive nature and limited impact.

    Given the substantial morbidity and mortality associated with such outbreaks, a literature review was conducted as a basis for re-evaluating this policy.

    Methods

    Reports of supplementary immunization activities that were performed to control measles outbreaks in middle or low income countries were identified.

    The impact of the immunization activities on the course of each outbreak was evaluated by examining the data provided.

    Results

    Of 66 reports detailing a measles outbreak in a middle or low income country, 17 described supplementary immunization activities which included seven'non-selective'immunization campaigns, three'selective'campaigns and one use of an early 2-dose schedule.

    Eight of the reports commented on the impact of the response, five of which reported a reduction in outbreak morbidity.

    Only one of the reports, from an isolated island outbreak, provided sufficient data to support a possible reduction in outbreak-associated morbidity.

    Conclusions

    There are limited data on the impact of measles outbreak immunization activities from developing countries.

    The available data do not support a change in the WHO recommended strategy for conducting a limited, if any, immunization response to such outbreaks. (...)

    Mots-clés Pascal : Vaccination, Rougeole, Virose, Infection, Programme sanitaire, Prévention, Evaluation, Transmission, Epidémie, Homme, Pays en développement, Epidémiologie

    Mots-clés Pascal anglais : Vaccination, Measles, Viral disease, Infection, Sanitary program, Prevention, Evaluation, Transmission, Epidemic, Human, Developing countries, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0350421

    Code Inist : 002B05A02. Création : 12/09/1997.