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  1. Differences in diagnostic criteria for gastric carcinoma between Japanese and Western pathologists.

    Article - En anglais

    Background There have been many studies on gastric carcinoma in populations with contrasting cancer risks.

    We aimed to find out whether the criteria for the histological diagnosis of early gastric carcinoma were comparable in Western countries and Japan.

    Methods Eight pathologists from Japan, North America, and Europe individually reviewed 35 microscope slides : 17 gastric biopsy samples and 18 endoscopic mucosal resections taken from 17 Japanese patients with lesions ranging from early gastric cancer to adenoma, dysplasia, and reactive atypia.

    The pathologists were given a list of pathological criteria and a form on which they were asked to indicate the criteria on which they based each diagnosis.

    Findings For seven slides most Western pathologists diagnosed low-grade adenoma/dysplasia, whereas the Japanese diagnosed definite carcinoma in four slides, suspected carcinoma in one, and adenoma in only two.

    Of 12 slides with high-grade adenoma/dysplasia according to most Western pathologists the Japanese gave the diagnosis of definite carcinoma in 11 and suspected in one.

    Of six slides showing high-grade adenoma/dysplasia with suspected carcinoma according to most Western pathologists the Japanese diagnosed definite carcinoma in all.

    There were no major differences in the diagnoses of three slides showing reactive epithelium and seven slides with clearly invasive carcinoma. (...)

    Mots-clés Pascal : Carcinome, Estomac, Diagnostic, Histopathologie, Facteur prédictif, Etude comparative, Incidence, Japon, Asie, Monde Ouest, Spécialiste information, Homme, Tumeur maligne, Appareil digestif pathologie, Estomac pathologie

    Mots-clés Pascal anglais : Carcinoma, Stomach, Diagnosis, Histopathology, Predictive factor, Comparative study, Incidence, Japan, Asia, Western countries, Information scientist, Human, Malignant tumor, Digestive diseases, Gastric disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0342593

    Code Inist : 002B13B01. Création : 12/09/1997.