Effect of pharmaceutical care on optimum colestipol treatment in elderly hypercholesterolemic veterans.
We conducted a prospective trial to determine whether a formal, integrated pharmaceutical care plan can enhance patient acceptance and compliance with colestipol therapy and improve outcomes.
Forty patients with hypercholesterolemia were equally divided and assigned to either a usual care or pharmaceutical care group.
In the pharmaceutical care group compared with the usual care group, after 52 weeks, colestipol therapy resulted in a greater reduction in total cholesterol (12.5% vs 7.3%), low-density lipoprotein cholesterol (LDL-C ; 16% vs 9.4%), and LDL-C : high-density lipoprotein cholesterol (HDL-C) ratio (24.4% vs 12.2%, p<0.05).
The percentage of patients who achieved their LDL-C goal at week 52 was much greater in the pharmaceutical care group (29.4%) than in the usual care group (5.0%, p<0.05).
Comanagement by a physician and a pharmacist of hypercholesterolemic veterans treated with colestipol can enhance patient acceptance of the drug, LDL-C reduction, and achievement of therapeutic goals.
Mots-clés Pascal : Colestipol, Hypolipémiant, Vieillard, Homme, Hypercholestérolémie, Chimiothérapie, Traitement, Efficacité traitement, Prospective, Observance médicamenteuse, Pharmacien, Activité professionnelle, Voie orale, Relation médecin malade, Lipide, Métabolisme pathologie, Dyslipémie, Hyperlipoprotéinémie, Soin pharmaceutique, Suivi thérapeutique médicamenteux
Mots-clés Pascal anglais : Colestipol, Antilipemic agent, Elderly, Human, Hypercholesterolemia, Chemotherapy, Treatment, Treatment efficiency, Prospective, Drug compliance, Chemist, Professional activity, Oral administration, Physician patient relation, Lipids, Metabolic diseases, Dyslipemia, Hyperlipoproteinemia, Pharmaceutical care, Therapeutic drug monitoring
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0339512
Code Inist : 002B02N. Création : 12/09/1997.