Internal exposure to hazardous substances of persons from various continents : Investigations on exposure to different organochlorine compounds.
The aim of the study was to investigate the concentration of organochlorine compounds of environmental-medical relevance in biological materials from refugees with regard to their countries of origin and to compare these concentrations with the internal exposure of the German general population.
During medical examination after entry to Germany specimens could be taken from the refugees to determine the following parameters of biological monitoring : 1.1-dichloro-2,2-bis (-chlorophenyl) - ethylene (DDE-P), polychlorinated biphenyls (PCB-P), pentachlorophenol (PCP-P) and the beta-and gammahexachlorocyclohexanes (bêta-HCH-P, gamma-HCH-P) in plasma and the excretion of chlorophenols (4-MCP-U, 2,4-DCP-U, 2,5-DCP-U, 2,4,5-TCP-U, 2,4,6-TCP-U, 2,3,4,5-TeCP-U, 2,3,5,6-TeCP-U) in urine.
One hundred and three men (13 from former Yugoslavia, 29 from the former USSR, 33 Africans and 28 Asians) ranging from 16 to 53 years of age (median 27 years) were investigated.
Thirty four male Germans without occupational exposure to these substances and a similar age structure (age 25-36 years ; median 26 years) served as a control group.
A much higher level of internal exposure was found for the DDT metabolite, DDE, for those persons from Asia, the former USSR and Africa compared with the German controls (medians : l6.9 mug/l, 11.9 mug/l, 10.9 mug/l and 1.1 mug/1).
The levels of PCB in plasma were below the detection limit in the majority of refugees. (...)
Mots-clés Pascal : DDT, Biphényle(polychloro), HCH, Phénol(polychloro), Organochloré, Pollution, Environnement, Surveillance biologique, Taux, Urine, Immigrant, Lieu naissance, Allemagne, Europe, Homme
Mots-clés Pascal anglais : DDT, Polychlorobiphenyl, HCH, Organochlorine compounds, Pollution, Environment, Biological monitoring, Rate, Urine, Immigrant, Birth place, Germany, Europe, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0336624
Code Inist : 002B03M01. Création : 12/09/1997.