Congestive heart failure in old age : prevalence, mechanisms and 4-year prognosis in the Helsinki Ageing Study.
To examine the prevalence, underlying diseases, abnormalities of left ventricular function and prognosis in congestive heart failure (CHF) of old age.
A population-based clinical and echocardiographic study with a 4-year mortality follow-up.
Five hundred and one individuals born in 1904,1909 and 1914 (367 women).
Main outcome measures
Presence of CHF by clinical and chest radiograph criteria ; left ventricular size and systolic function by echocardiography ; grade of aortic and mitral valve lesions by Doppler echocardiography ; 4-year total and cardiovascular mortality.
Forty-one of 501 participants (8.2%) had CHF.
Ischaemic heart disease (54%), hypertension (54%) and moderate-to-severe mitral or aortic valve disease (51%) were the main underlying conditions ; 90% of patients had one or more of these diseases.
Most individuals with CHF (28 of 39 patients, 72%) had normal left ventricular contractions at echocardiography.'Diastolic CHF'defined as CHF with normal systolic left ventricular function and no regurgitant valve disease, was found in 51% (20 of 39 patients).
The relative 4-year risk for death associated with CHF, adjusted for age and sex, was 2.1 (95% confidence interval 1.3-3.4) for all-cause mortality and 4.2 (CI 1.9-5.6) for cardiovascular mortality.
The prevalence of CHF in a population aged 75-86 years is approximately 8%. (...)
Mots-clés Pascal : Insuffisance cardiaque, Mortalité, Finlande, Europe, Fonction ventriculaire gauche, Echocardiographie, Dopplérométrie, Prévalence, Epidémiologie, Pronostic, Vieillard, Homme, Appareil circulatoire pathologie, Cardiopathie, Exploration ultrason
Mots-clés Pascal anglais : Heart failure, Mortality, Finland, Europe, Left ventricle performance, Echocardiography, Doppler ultrasound study, Prevalence, Epidemiology, Prognosis, Elderly, Human, Cardiovascular disease, Heart disease, Sonography
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0330761
Code Inist : 002B12A01. Création : 12/09/1997.