A method is proposed for computing the coverage required to prevent epidemics by age-specific vaccination schedules.
The method applies in a very general setting and provides explicit expressions in many cases.
It can accommodate vaccination doses administered at different ages, heterogeneity among individuals of different ages, a community structured into households, and waning of vaccine-induced immunity.
A comparison of results for two specific community settings, with analogous parameter values, indicates that the immunity coverage required to prevent epidemics in a community of households is less than that required for a community of uniformly mixing individuals.
Mots-clés Pascal : Epidémie, Prévention, Calendrier vaccination, Age, Homme, Dosage, Etude comparative, Immunité, Traitement communautaire, Analyse mathématique
Mots-clés Pascal anglais : Epidemic, Prevention, Vaccination schedule, Age, Human, Assay, Comparative study, Immunity, Community treatment, Mathematical analysis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0330192
Code Inist : 002B30A01C. Création : 12/09/1997.