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  1. ICD-10 mild cognitive disorder : Its outcome three years later.

    Article - En anglais


    The aims were to (i) report the outcome of mild cognitive disorder (MCD) 3.6 years after initial interview and diagnosis ; (ii) identify predictors of new cases of MCD.

    The hypotheses were that (i) persons with MCD are more likely to develop dementia than those without MCD ; (ii) symptoms of anxiety or depression predict MCD caseness at follow-up.


    Longitudinal cohort study.


    Community of elderly people (age 70-97 years).


    612 of 897 elderly subjects (mean 76 years) were reinterviewed.

    Of the 36 MCD cases originally identified, 25 were available at follow-up. 24 incident cases of MCD were identified.

    Main outcome measures

    ICD-10 dementia, DSM-III-R dementia, ICD-10 mild cognitive disorder diagnoses made by the Canberra Interview for the Elderly, tests of anxiety, depression, neuroticism and cognitive performance.

    Main results

    Of the original 25 MCD cases available at follow-up, two had a diagnosis of MCD, and three had a diagnosis of both ICD-10 and DSM-III-R dementia.

    The prevalence of MCD and DSM-III-R dementia at follow-up was no greater for MCD cases diagnosed at initial interview than in normal subjects at initial interview.

    There was, however, an increased prevalence of ICD-10 dementia among original MCD cases.

    At initial interview and at follow-up MCD cases were more anxious and depressed but had similar cognitive performance to normals.

    For incident cases of MCD the only significant predictor was age.



    Mots-clés Pascal : Etude longitudinale, Evolution, Trouble cognition, Facteur risque, Névrotisme, Personnalité, Démence, Trouble anxieux, Etat dépressif, Trouble humeur, International Classification of Diseases 10, Prévalence, Epidémiologie, Vieillard, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative, Plainte mnésique

    Mots-clés Pascal anglais : Follow up study, Evolution, Cognitive disorder, Risk factor, Neuroticism, Personality, Dementia, Anxiety disorder, Depression, Mood disorder, International Classification of Diseases 10, Prevalence, Epidemiology, Elderly, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease, Memory complaint

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0329771

    Code Inist : 002B18E. Création : 12/09/1997.