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  1. Evaluation of the Q16 questionnaire on neurotoxic symptoms and a review of its use.

    Article - En anglais

    Objectives-The questionnaire 16 (Q16) is commonly used to study prevalences of neurotoxic symptoms among workers exposed to organic solvents.

    It has also been recommended that exposed workers reporting more than six symptoms should be referred for further examination of possible chronic toxic encephalopathy.

    It would be useful to know whether symptoms reported in the questionnaire also reflect impairment of similar functions measured with objective or semiobjective methods in a formerly highly exposed group.

    Methods-135 painters and 71 carpenters answered the Q16, were interviewed about symptoms compatible with an organic brain damage, and took a battery of psychometric tests.

    A subsample of 52 painters and 45 carpenters were interviewed for psychiatric diagnosis according to Diagnostic and Statistical Manual for Mental Disorders, 3rd version (DSM III) and their vibration thresholds in hands and feet were measured.

    The entire group was followed up in the register of diagnoses at early retirement 1971-93.

    The lifetime exposure to organic solvents was assessed.

    Current exposure to organic solvents was found to be low or none.


    The prevalence of people with more than six symptoms in the Q16 rose with increasing cumulative exposure to solvents.

    The sensitivity of the questionnaire (more than six symptoms) to detect people who were assessed to exhibit symptoms compatible with an organic brain damage was only 38%. (...)

    Mots-clés Pascal : Solvant organique, Exposition professionnelle, Toxicité, Encéphalopathie, Questionnaire, Encéphalique organique syndrome, Trouble psychiatrique, Psychométrie, Dépistage, Homme, Symptomatologie, Evaluation, Peintre en bâtiment, Médecine travail, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Suède, Europe, Charpentier

    Mots-clés Pascal anglais : Organic solvent, Occupational exposure, Toxicity, Encephalopathy, Questionnaire, Organic brain syndrome, Mental disorder, Psychometrics, Medical screening, Human, Symptomatology, Evaluation, House painter, Occupational medicine, Nervous system diseases, Central nervous system disease, Cerebral disorder, Sweden, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0327241

    Code Inist : 002B03L04. Création : 12/09/1997.