Objectives-To determine the prevalence of latex sensitisation among a large group of healthcare workers, study the occupational and non-occupational factors associated with latex allergy, and characterise latex exposure in air and by gloves.
Methods-All 2062 employees of a general hospital in Hamilton, Ontario, Canada who regularly used latex gloves were invited to participate in a cross sectional survey, representing the baseline phase of a prospective cohort morbidity study.
Attempts were made to recruit employees who were diagnosed with latex allergy before the survey.
Glove extracts were assayed for antigenic protein, and area and personal air samples were obtained on two occasions (summer and winter) to estimate exposure to airborne latex protein.
A questionnaire on medical and occupational information was administered by an interviewer.
Skin prick tests were performed with latex reagents, three common inhalants, and six foods.
The mean (SD) latex protein concentrations were 324 (227) mug/g in powdered surgical gloves and 198 (104) mug/g in powdered examination gloves.
Personal latex aeroallergen concentrations ranged from 5 to 616 ng/m3.
The prevalence of positive latex skin tests was 12.1% (95% confidence interval (95% CI) 10.3% to 13.9%). This prevalence did not vary by sex, age, hospital, or smoking status but subjects who were latex positive were significantly more likely to be atopic (P<0.01). (...)
Mots-clés Pascal : Latex, Exposition professionnelle, Toxicité, Allergie, Personnel sanitaire, Milieu hospitalier, Homme, Epidémiologie, Ontario, Canada, Amérique du Nord, Amérique, Médecine travail, Gant, Pollution air, Pollution intérieur, Immunopathologie
Mots-clés Pascal anglais : Latex, Occupational exposure, Toxicity, Allergy, Health staff, Hospital environment, Human, Epidemiology, Ontario, Canada, North America, America, Occupational medicine, Glove, Air pollution, Indoor pollution, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0327240
Code Inist : 002B06C04. Création : 12/09/1997.