In late April 1995, an outbreak of a poorly defined respiratory illness related to the ingestion of leaves of Sauropus androgynus was observed in southern Taiwan.
To further evaluate the association between S. androgynus and bronchiolitis obliterans syndrome, a hospital-based case-control study was conducted with one case group and three different control groups at Veterans General Hospital-Kaohsiung between April and September 1995.
A total of 54 cases (50 females, 4 males), 54 age-and sex-matched neighborhood controls, 54 matched routine physical check-up controls, and 54 matched self-referred patron controls (who had ingested S. androgynus yet without obstructive physiology) were interviewed for clinical symptoms, history of S. androgynus consumption, and potential confounding factors.
All 54 cases (100%) ingested S. androgynus compared with only five (9%) neighborhood controls (matched odds ratio (OR) incalculable, p<0.001) and two (4%) physical check-up controls (matched OR incalculable, p<0.001).
In the univariate analysis of 54 cases and 54 self-referred patron controls, factors associated with an increased risk of bronchiolitis obliterans syndrome were methods of food preparation (uncooked juice vs. stir fried or boiled dishes, matched OR 10.3 (95% confidence interval (CI) 1.3-84.4)) ; preparer of the S. androgynus-containing food (vendor only vs. patient only or patient plus vendor, matched OR 2.8 (95% CI 1.1-7.1)) ; total S. (...)
Mots-clés Pascal : Bronchiolite oblitérante, Epidémiologie, Homme, Euphorbiaceae, Dicotyledones, Angiospermae, Spermatophyta, Alimentation, Origine végétale, Toxicité, Taiwan, Asie, Feuille végétal, Etude cas témoin, Appareil respiratoire pathologie, Bronche pathologie, Sauropus androgynus
Mots-clés Pascal anglais : Bronchiolitis obliterans, Epidemiology, Human, Euphorbiaceae, Dicotyledones, Angiospermae, Spermatophyta, Feeding, Plant origin, Toxicity, Taiwan, Asia, Plant leaf, Case control study, Respiratory disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0315888
Code Inist : 002B03H. Création : 12/09/1997.