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  1. Hazard proximities of childhood cancers in Great Britain from 1953-80.

    Article - En anglais

    Study objectives

    Firstly, to examine relationships between the birth and death addresses of children dying from leukaemia and cancer in Great Britain, and the sites of potential environmental hazards ; and secondly to measure relative case densities close to, and at increasing distances from, different hazard types.


    Home address postcodes (PCs) and their map coordinates were identified at birth and at death in children who died from leukaemia or cancer.

    Potentially hazardous industrial addresses and PCs were listed from business and other directories, and map coordinates obtained from the Central Postcode Directory or else located directly on Ordnance Survey (OS) maps.

    Railway lines and motorways were digitised from OS maps.

    Numbers of deaths (and births) at successive radial distances from these hazards were counted and compared with expected numbers.

    The latter were based on a count of all PCs at similar distances.

    Relative case density ratios at successive distances from the hazards were obtained from observed and expected numbers, aggregated over similar sites.

    This was repeated for different hazard types and results were tested for evidence of systematic centrifugal case density gradients.

    Participants and setting

    All 22 458 children dying from leukaemia or cancer aged 0-15 years, in England, Wales, and Scotland, between 1953 and 1980. (...)

    Mots-clés Pascal : Tumeur maligne, Leucémie, Enfant, Homme, Proximité, Zone industrielle, Pollution air, Toxicité, Epidémiologie, Santé et environnement, Grande Bretagne, Royaume Uni, Europe, Mortalité, Industrie, Hémopathie maligne

    Mots-clés Pascal anglais : Malignant tumor, Leukemia, Child, Human, Proximity, Industrial area, Air pollution, Toxicity, Epidemiology, Health and environment, Great Britain, United Kingdom, Europe, Mortality, Industry, Malignant hemopathy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0313422

    Code Inist : 002B04B. Création : 12/09/1997.