Prospective radiographic and clinical analysis of a consecutive unselected population of persons with Marfan Syndrome.
To determine cervical spine abnormalities present in tne Marfan population compared with that seen in the general population. of Background Data.
In the treatment of a large population of patients with Marfan Syndrome, three serious cervical spine disorders were noted.
To the authors'knowledge, no report of cervical abnormalities in patients with Marfan Syndrome exists in the literature.
Therefore, the cervical spine in these patients was studied in a systematic fashion.
An unselected group of 104 consecutive patients with Marfan Syndrome seen at a medical genetics follow-up examination underwent lateral neutral and flexion-extension cervical spine radiographs.
Parameters of alignment, size, and stability were measured.
Patients with Marfan Syndrome aged 35-45 years and matched controls were given a pain questionnaire to complete.
The prevalence of focal kyphosis was 16%. A large number of patients with Marfan Syndrome (54%) had increased atlantoaxial translation.
The preadolescent Marfan population had a greater range of motion than either the adolescent or adult populations.
The Marfan population has an increased radiographic prevalence of basilar impression (36%). and the odontoid height (3.69 ± 0.53 cm) was larger than reported norms (2.34 ± 0.22 cm). (...)
Mots-clés Pascal : Marfan syndrome, Homme, Exploration, Radiographie, Morphologie, Complication, Déformation, Os, Rachis cervical, Epidémiologie, Prévalence, Etude longitudinale, Tissu élastique pathologie, Tissu conjonctif pathologie, Maladie héréditaire, Maladie système, Radiodiagnostic, Système ostéoarticulaire pathologie, Rachis pathologie
Mots-clés Pascal anglais : Marfan syndrome, Human, Exploration, Radiography, Morphology, Complication, Deformation, Bone, Cervical spine, Epidemiology, Prevalence, Follow up study, Elastic tissue disease, Connective tissue disease, Genetic disease, Systemic disease, Radiodiagnosis, Diseases of the osteoarticular system, Spine disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0310973
Code Inist : 002B07. Création : 15/07/1997.