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  1. Prevalence of and risk factors for Helicobacter pylori infection in a multi-racial dyspeptic Malaysian population undergoing endoscopy.

    Article, Communication - En anglais

    Symposium on gastroenterology and hepatology in the Asian-Pacific Region - Japanese Society of Gastroenterology JSGE General Meeting. Nagoya (JPN), 1995/11/23.

    The aim of the present study was to determine the risk factors for Helicobacter pylori in a dyspeptic Malaysian population.

    A cross-sectional survey of 1060 consecutive patients presenting with dyspepsia at the Endoscopic Unit, University Hospital, Kuala Lumpur, Malaysia from January 1994 to July 1995 was undertaken.

    All patients answered a detailed questionnaire and underwent endoscopy, with two antral biopsies taken for diagnosis of H. pylori using a rapid urease test.

    An overall H. pylori prevalence of 49.0% was recorded.

    Helicobacter pylori prevalence in relation to the major endoscopic diagnoses were as follows :

    • non-ulcer dyspepsia (NUD) 31.2% ;

    • duodenal ulcer (DU) 91.4% ;

    • and gastric ulcer (GU) 74.1%. The prevalence among the races were as follows : Malay 16.4% ;

    • Chinese 48.5% ;

    • and Indians 61.8%. Multiple logistic regression analysis identified the following as independent risk factors :>45 years old 1.5 (1.1,2.0) ;

    • male gender 1.6 (1.2,2.1) ;

    • ethnic group : Chinese 2.5 (1.7,3.7) ;

    • Indians 4.9 (3.2,7.5) ;

    • level of education : low 2.3 (1.5,3.5) ;

    • middle 1.7 (1.1,2.6) ;

    • and smoking 1.6 (1.2,2.3).

    Analysis was also performed on DU, GU and non-UD patients separately ; in both DU and GU patients, H. pylori prevalence was high regardless of age, sex, race or level of education.

    However, in DU patients, Indian race had an independent risk factor (Odds ratio=7.8 (1.2,48.4)). (...)

    Mots-clés Pascal : Dyspepsie, Diagnostic, Gastroscopie, Facteur risque, Gastrite, Campylobactériose, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Ulcère, Gastroduodénal, Epidémiologie, Homme, Malaisie, Asie, Appareil digestif pathologie, Endoscopie, Estomac pathologie, Intestin pathologie

    Mots-clés Pascal anglais : Dyspepsia, Diagnosis, Gastroscopy, Risk factor, Gastritis, Campylobacter infection, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Ulcer, Gastroduodenal, Epidemiology, Human, Malaysia, Asia, Digestive diseases, Endoscopy, Gastric disease, Intestinal disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0310918

    Code Inist : 002B30A01A2. Création : 15/07/1997.