Sensitization to inhaled allergens as a risk factor for asthma and allergic diseases in Chinese population.
Allergen sensitization is associated with asthma and allergic disease in children, but such a relationship has not been confirmed in Chinese populations.
The objective of this study was to evaluate the effects of allergen sensitization and family history of atopy on asthma and allergic disease in Chinese schoolchildren from three southeast Asian populations.
Written questionnaires on respiratory and allergic symptoms were completed by parents of children of secondary-school age (age range 12 to 18 years) in Hong Kong (n=1062), Kota Kinabalu in eastern Malaysia (n=409), and San Bu in southern China (n=737).
A subsample of schoolchildren underwent skin prick testing to common inhalant allergens (Hong Kong 471 children, Kota Kinabalu 321, San Bu 647).
The prevalence of asthma and allergic disease in schoolchildren was highest in Hong Kong, intermediate in Kota Kinabalu, and lowest in San Bu.
However, the overall rate of atopic sensitization was similar in the three populations (49% to 63%). House dust mite and cockroach were the two most common allergens causing sensitization and these gave rise to more than 95% of the positive skin test results in all three populations.
By regression analysis, mite allergy was associated with rhinitis and asthma in all three populations, and a family history of asthma, rhinitis, or eczema was strongly associated with respective symptoms in the subjects. (...)
Mots-clés Pascal : Asthme, Facteur risque, Epidémiologie, Poussière maison, Dermatophagoides pteronyssinus, Pyroglyphidae, Acaridida, Acariformes, Acari, Arachnida, Arthropoda, Invertebrata, Allergène, Blattellidae, Dictyoptera, Insecta, Sensibilisation, Logement habitation, Chinois, Hong Kong, Asie, Malaisie, Chine, Enfant, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Blatte, Pneumallergène
Mots-clés Pascal anglais : Asthma, Risk factor, Epidemiology, House dust, Dermatophagoides pteronyssinus, Pyroglyphidae, Acaridida, Acariformes, Acari, Arachnida, Arthropoda, Invertebrata, Allergen, Blattellidae, Dictyoptera, Insecta, Sensitization, Housing, Chinese, Hong Kong, Asia, Malaysia, China, Child, Human, Respiratory disease, Obstructive pulmonary disease, Aeroallergen
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0309728
Code Inist : 002B06C02. Création : 15/07/1997.