Symposium "Community Respiratory Viral Infections in the Immunocompromised Host". .
Among immunocompromised adults, such as bone marrow transplant recipients, more than half of respiratory viral infections are complicated by pneumonia, with an associated mortality rate>50%. Nosocomial transmission of respiratory viral pathogens, such as respiratory syncytial virus (RSV) and influenza, in the immunocompromised patient has been reported frequently and usually occurs during a community outbreak.
In view of the poor outcome in this subset of patients, intensive efforts should be directed at instituting prevention measures that would interrupt nosocomial transmission.
At M.D. Anderson Cancer Center, a multifaceted infection control strategy resulted in a significant decrease in and almost complete interruption of the nosocomial transmission of RSV infections in immunocompromised patients over a 3-year period (1994-1996).
For influenza virus, special emphasis should be given to vaccination of hospital personnel before the influenza season to prevent and control nosocomial transmission.
In highly immunocompromised patients, prophylactic use of antiviral agents should be considered during an outbreak or when the frequency of nosocomial transmission is high.
An aggressive multifaceted infection control strategy appears to be effective in reducing the frequency of nosocomial transmission of respiratory viral infections in immunocompromised patients.
Universal and timely influenza vaccination of hospital personnel who care for immunocompromised patients is necessary.
Mots-clés Pascal : Virose, Infection, Appareil respiratoire, Infection nosocomiale, Immunodéficit, Association, Incidence, Prévention, Service hospitalier, Immunoprophylaxie, Homme, Relation soignant soigné, Appareil respiratoire pathologie, Immunopathologie
Mots-clés Pascal anglais : Viral disease, Infection, Respiratory system, Nosocomial infection, Immune deficiency, Association, Incidence, Prevention, Hospital ward, Immunoprophylaxis, Human, Health staff patient relation, Respiratory disease, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0309675
Code Inist : 002B05C02C. Création : 15/07/1997.