Symposium "Community Respiratory Viral Infections in the Immunocompromised Host". .
Respiratory viruses, particularly influenza viruses, respiratory syncytial virus (RSV), parainfluenza viruses, and adenoviruses, are ubiquitous pathogens among humans, especially among young children.
However, relatively little is known about the impact of these common infections on individuals with the human immunodeficiency virus (HIV).
A review of the literature identifies three key areas that need further exploration.
First, moderate-to-severe and even fatal lower respiratory viral illnesses in HIV-infected individuals have been reported.
In general, the clinical presentation of these respiratory viral infections in persons with HIV infection is similar to their presentation in individuals without HIV infection.
The major exception is the occurrence of fulminant, and often fatal, disseminated adenovirus infection in adults and children with HIV disease.
Despite these reports, no information is available regarding the frequency of moderate-to-severe respiratory viral illnesses in individuals with HIV infection.
Epidemiologic studies of respiratory viral illnesses in cohorts of HIV-infected adults and children are needed.
Second, prolonged shedding of respiratory viruses for weeks and even months has been documented in HIV-infected adults and children.
The frequency of prolonged shedding in this population has not been well defined, but data from a small newborn cohort study suggest that, at least for RSV, prolonged shedding is common. (...)
Mots-clés Pascal : SIDA, Virose, Infection, Association, Infection communautaire, Appareil respiratoire, Epidémiologie, Facteur risque, Complication, Etiologie, Influenzavirus, Orthomyxoviridae, Virus, Immunoprophylaxie, Homme, Immunopathologie, Immunodéficit, Appareil respiratoire pathologie, Organisation santé
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Association, Community acquired infection, Respiratory system, Epidemiology, Risk factor, Complication, Etiology, Influenzavirus, Orthomyxoviridae, Virus, Immunoprophylaxis, Human, Immunopathology, Immune deficiency, Respiratory disease, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0309224
Code Inist : 002B05C02C. Création : 15/07/1997.