This research studied the relative conntribution of diabetes mellitus to the increased prevalence of tuberculosis in Hispanics.
A case-control study was conducted involving all 5290 discharges from civilian hospitals in California during 1991 who had a diagnosis of tuberculosis, and 37 366 control subjects who had a pnmary discharge diagnosis of deep venous thrombosis, pulmonary embolism, or acute appendicitis.
Risk of tuberculosis was estimated as the odds ratio (OR) across race/ethnicity, with adjustment for other factors.
Diabetes mellitus was found to be an independent risk factor for tuberculosis.
The association of diabetes and tuberculosis was higher among Hispanics (adjusted OR [ORadj]=2.95 : 95% confidence interval [Cl]=2.61,3.33) than among non-Hispanic Whites (ORadj=1.31 ; 95% Cl=1.19,1.45) ; among non-Hispanic Blacks, diabetes was not found to be associated with tuberculosis (ORadj=0.93 : 95% Cl=0.78. 1.09).
Among Hispanics aged 25 to 54, the estimated risk of tuberculosis attributable to diabetes (25.2% was equivaient to that attributable to HIV infection (25.5%). Conclusions.
Diabetes mellitus remains a significant risk factor for tuberculosis in the United States.
The association is especially notable in middle-aged Hispanics.
Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Epidémiologie, Facteur risque, Diabète, Homme, Ethnie, Latinoaméricain, Prévalence, Californie, Etats Unis, Amérique du Nord, Amérique, Appareil respiratoire pathologie, Endocrinopathie, Hispanique
Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Epidemiology, Risk factor, Diabetes mellitus, Human, Ethnic group, Latinamerican, Prevalence, California, United States, North America, America, Respiratory disease, Endocrinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 97-0307342
Code Inist : 002B05B02E. Création : 15/07/1997.