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  1. Enrolment of a population-based cohort of newborns at higher risk of developing a chronic condition : The EDEN study.

    Article - En anglais


    To describe the methods used at birth to recruit a population-based cohort of newborns of all birthweights at higher risk of having a chronic condition, and to present baseline results.


    Screening of all newborns at hospital discharge for five non-exclusive criteria : (1) low birthweight (LBW), (2) congenital anomalies or genetic disease, (3) specified conditions associated with a high probability of chronicity, (4) referral to a neonatal intensive care unit (NICU), (5) or defined social problems.

    Calculation of Hobel risk scores for children satisfying =1 criterion.


    All 6477 live births delivered in the 19 maternity hospitals of a geographically defined region (Vaud, Switzerland) to resident mothers in 1993-1994.


    Twelve per cent (n=760) of newborns met = 1 criterion : 6.3% of all newborns had an LBW (criterion 1), 2.4% had a birth defect, 0.9% met criterion (3), 4.4% stayed in an NICU and 1.6% had serious social problems.

    Hobel prenatal score was high (=10 points) for 41% of children with =1 criterion, the intrapartum score for 87% and the neonatal score for 68%. Conclusions.

    Most newborns identified by the above simple criteria also had elevated perinatal risks. (...)

    Mots-clés Pascal : Chronicité, Maladie, Nouveau né pathologie, Gestation pathologie, Handicap, Epidémiologie, Facteur risque, Nouveau né, Homme, Suisse, Europe, Etude cohorte

    Mots-clés Pascal anglais : Chronicity, Disease, Newborn diseases, Pregnancy disorders, Handicap, Epidemiology, Risk factor, Newborn, Human, Switzerland, Europe, Cohort study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0289514

    Code Inist : 002B20F02. Création : 15/07/1997.