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  1. Serum uric acid and its correlates in Chinese adult populations, urban and rural, of Beijing.

    Article - En anglais

    Background

    Reports on serum uric acid (SUA) levels in Chinese populations are sparse, but there is evidence that hyperuricaemia and gout are not uncommon.

    This paper characterizes SUA levels, their correlates, and their relationship to blood pressure (BP) and prevalent high blood pressure (HBP) for urban and rural adult population samples in north China.

    Methods

    In 1987-1988, a cross-sectional study was carried out, using standardized methods, on men and women aged 40-58 in a Beijing area urban steel mill (N=2013) and on rural farms (1507).

    Main outcome measures were SUA, systolic and diastolic blood pressure (SBP, DBP), and prevalent HBP (SBP = 140 or DBP = 90 mmHg or receiving an antihypertensive drug).

    Results

    Mean SUA levels for men were 5.75 mg/dl in urban and 5.58 mg/dl in rural settings ; for women, 4.67 and 4.48 mg/dl.

    Mean values were higher with age in women, but not in men.

    Age-standardized prevalence rates of HBP were significantly higher in upper SUA strata (men = 7.00, women =6.00 mg/dl) than lower SUA strata both with and without inclusion of those on antihypertensive drugs.

    Mean SUA levels were correspondingly higher in hypertensive than non-hypertensive people.

    In multiple regression analyses, body mass index and serum triglycerides were strongly associated with SUA.

    Also SBP, DBP, and HBP were generally associated with SUA for the whole population sample, with smaller coefficients after excluding those on antihypertensive drugs. (...)

    Mots-clés Pascal : Appareil circulatoire pathologie, Pression sanguine, Urique acide, Plasma sanguin, Epidémiologie, Facteur risque, Homme, Chine, Asie

    Mots-clés Pascal anglais : Cardiovascular disease, Blood pressure, Uric acid, Blood plasma, Epidemiology, Risk factor, Human, China, Asia

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0289512

    Code Inist : 002B12B06. Création : 15/07/1997.