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  1. Predictors of recurrent febrile seizures : A prospective cohort study.

    Article - En anglais

    Objectives 

    To define the risk and identify predictors of single and multiple recurrent febrile seizures.

    Methods 

    Children (n=428) with first febrile seizures were prospectively identified and followed for 2 or more years.

    Parents were interviewed soon after their children's first febrile seizure and were called every 3 months to ascertain recurrent febrile seizures.

    Medical records of first and recurrent seizures were reviewed for additional information.

    Results 

    A total of 136 children (31.8%) experienced recurrent seizures : 73 (17.1%) had only 1 recurrence, 38 (8.9%) had 2 recurrences, and 25 (5.8%) had 3 or more recurrences.

    Young age at onset, a history of febrile seizures in a first-degree relative, low degree of fever while in the emergency department, and a brief duration between the onset of fever and the initial seizure were strong independent predictors of recurrent febrile seizures.

    With these 4 factors combined, it is possible to define groups of children having very high and very low probabilities of having any recurrences (>70% vs<20%), having 2 or more recurrences (>60% vs<10%), and having 3 or more recurrences (12% vs about 0%). In children who had at least 1 recurrence, age at the time of the first recurrence and a family history of epilepsy were predictors of subsequent recurrences.

    Conclusions 

    In children who have had a first febrile seizure, recurrences are common. (...)

    Mots-clés Pascal : Convulsion fébrile, Enfant, Homme, Nourrisson, Récidive, Facteur risque, Facteur prédictif, Etude longitudinale, Etude cohorte, Age, Epidémiologie, Fièvre, Trouble neurologique

    Mots-clés Pascal anglais : Febrile convulsion, Child, Human, Infant, Relapse, Risk factor, Predictive factor, Follow up study, Cohort study, Age, Epidemiology, Fever, Neurological disorder

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0288749

    Code Inist : 002B17A03. Création : 15/07/1997.