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  1. Urinary tract infections in girls : the cost-effectiveness of currently recommended investigative routines.

    Article - En anglais

    Current recommendations for the universal investigation of urinary tract infection (UTI) in children by ultrasonography, voiding cystourethrography, and dimercaptosuccinic acid renal scan (and sometimes intravenous pyelography as well) are not based on any convincing evidence as to the necessity or effectiveness of such a routine.

    Over 8% of all girls will have a UTI during childhood.

    About 87 individuals in a million will develop end-stage renal disease (ESRD) by the age of 60 years, caused in about 9% by pyelonephritis (PN) or reflux nephropathy.

    From these statistics, the maximal risk of a first diagnosed UTI progressing to ESRD is approximately 1 : 10,000.

    The risk of developing hypertension following a first UTI in childhood, without eventual evolution to ESRD, appears to be very small.

    The cost of the widely recommended routine imaging procedures ranges from U.S. $ 355 in Britain to U.S. $ 1,090 in the United States.

    The minimal cost of preventing a single progression to ESRD by early diagnosis of underlying pathology - if this were possible in all cases - would range between U.S. $ 5 million in Britain and U.S. $ 15 million in the United States.

    Since in many instances progressive renal damage can not be prevented, the true cost is considerably higher.

    Lower UTI in girls is a very common and, in most cases, benign finding in primary-care practice. (...)

    Mots-clés Pascal : Infection, Voie urinaire, Analyse coût efficacité, Economie santé, Evaluation, Echographie, Urographie, Tomodensitométrie, Etude comparative, Exploration, Diagnostic, Enfant, Homme, Femelle, Appareil urinaire pathologie, Voie urinaire pathologie, Exploration ultrason, Radiodiagnostic

    Mots-clés Pascal anglais : Infection, Urinary tract, Cost efficiency analysis, Health economy, Evaluation, Echography, Urography, Computerized axial tomography, Comparative study, Exploration, Diagnosis, Child, Human, Female, Urinary system disease, Urinary tract disease, Sonography, Radiodiagnosis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 97-0288258

    Code Inist : 002B24A05. Création : 15/07/1997.